Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients
Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients
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DOI：
10.1007/s13224-020-01335-3
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发表时间：
2020-07-07
影响因子：
0.7
通讯作者：
Bawa, Amarjeet
中科院分区：
文献类型：
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作者：
Nayak, Arun Harishchandra;Kapote, Deepali Swapnil;Bawa, Amarjeet
背景新型冠状病毒病（COVID-19）是我们今天面临的最具挑战性的健康危机。在这种流行病的背景下，研究这种感染对怀孕及其结果的影响变得至关重要。因此，本研究旨在评估COVID-19感染对孕产妇发病率和死亡率、产程以及新生儿结局的影响。材料与方法共有977名孕妇被纳入研究，从2020年4月1日至5月15日在三级保健医院。有141名女性COVID检测呈阳性，其余836名患者被纳入COVID阴性组。结果在两组进行了比较。结果2010年新冠肺炎孕妇感染率为14.43%。COVID阳性和COVID阴性组中通过LSCS分娩的患者（50%）多于COVID阴性组（47%）（p > 0.05）。在2例（1.52%）COVID阳性母亲的新生儿和15例（1.91%）COVID阴性母亲的新生儿中观察到低APGAR评分（0-3）。总的来说，大多数婴儿都很健康。在所有接受检测的婴儿中，有3名婴儿最初被检测为阳性，第5天再次检测，结果为阴性。结论COVID感染对妊娠期母婴结局无显著影响，无证据表明COVID-19感染存在垂直传播，但建议对这些婴儿进行长期随访。
Background The novel coronavirus disease (COVID-19) is the most challenging health crisis that we are facing today. Against the backdrop of this pandemic, it becomes imperative to study the effects of this infection on pregnancy and its outcome. Hence, the present study was undertaken to evaluate the effects of COVID-19 infection on the maternal morbidity and mortality, the course of labour as well as the neonatal outcome. Materials and Methods A total of 977 pregnant women were included in the study, from 1st April to 15th May 2020 at a tertiary care hospital. There were 141 women who tested COVID positive and remaining 836 patients were included in the COVID negative group. Findings were compared in both the groups. Results The incidence of COVID positive pregnant women was found to be 14.43%. More patients delivered by LSCS in the COVID positive and the COVID negative group (50%) as compared to COVID negative group (47%), (p > 0.05). Low APGAR score (0-3) was observed in 2(1.52%) neonates of COVID positive mothers and in 15 (1.91%) neonates of COVID negative mothers. Overall most of the babies were healthy. Out of all babies tested, 3 were detected positive initially which were retested on day 5 and were found to be negative. Conclusion There is no significant effect of COVID infection on maternal and foetal outcome in pregnancy and there is no evidence of vertical transmission of the COVID-19 infection but long-term follow-up of these babies is recommended.