Contraception, fecundity, and pregnancy in women with epilepsy: an update on recent literature.
Contraception, fecundity, and pregnancy in women with epilepsy: an update on recent literature.
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DOI：
10.1097/wco.0000000000001039
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发表时间：
2022-04-01
影响因子：
4.8
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中科院分区：
文献类型：
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照顾女性癫痫患者需要关于抗癫痫药物的潜在致畸性，与激素避孕药的相互作用以及妊娠结局的专业知识。近年来，对宫内暴露婴儿认知结果的理解有所改善。补充叶酸有助于减轻抗癫痫药物的认知致畸性。最近的更新提供了保证，癫痫发作频率往往保持稳定，整个怀孕。关于癫痫和抗癫痫药物对女性癫痫患者生殖力的影响，存在相互矛盾的证据。最近的研究强调了早期咨询避孕，怀孕和抗癫痫药物的风险和相互作用的重要性。需要更多的研究来了解癫痫妇女的生育能力。
Caring for women with epilepsy requires specialized knowledge about potential teratogenicity of anti-seizure medications, interactions with hormonal contraception, and pregnancy outcomes. There has been an improvement in understanding the cognitive outcomes of infants exposed in utero in recent years. Folic acid supplementation helps mitigate the cognitive teratogenicity of anti-seizure medications. Recent updates provide reassurance that seizure frequency tends to remain stable throughout pregnancy. There is conflicting evidence about the fecundity impact of epilepsy and antiseizure medications in women with epilepsy. Recent research highlights the importance of early counseling about the risks and interactions of contraception, pregnancy and anti-seizure medications. More research is needed to understand fertility in women with epilepsy.