CIRCULATORY AND METABOLIC EFFECTS OF OXYGEN IN MYOCARDIAL INFARCTION
CIRCULATORY AND METABOLIC EFFECTS OF OXYGEN IN MYOCARDIAL INFARCTION
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DOI：
10.1136/bmj.4.5627.360
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发表时间：
1968-01-01
影响因子：
105.7
通讯作者：
CAMERON, AJ
中科院分区：
文献类型：
--
作者：
KENMURE, ACF;MURDOCH, WR;CAMERON, AJ
本文观察了50例急性心肌梗塞病人吸入高浓度氧对循环和代谢的影响。测量心率、动脉血压、心输出量、血气分压、pH值、乳酸和丙酮酸水平。一般来说，吸氧会导致心输出量和每搏输出量下降，血压和全身血管阻力上升。在少数心输出量很低的患者中，输出量增加。即使在初始值较低的患者中，动脉血氧分压也大幅上升。经常出现的动脉血乳酸水平升高在吸氧后降低。这些影响的治疗意义进行了讨论。
The circulatory and metabolic effects of inhalation of oxygen in high concentration were investigated in 50 patients with acute myocardial infarction. The heart rate, arterial blood pressure, cardiac out-put, blood gas tensions, pH, and lactate and pyruvate levels were measured. In general, oxygen inhalation produced a fall in cardiac output and stroke volume and a rise in blood pressure and systemic vascular resistance. In a small number of patients with very low cardiac out-puts there was a rise in output. A substantial rise in arterial oxygen tension was obtained even in patients with low initial values. The raised arterial blood lactate levels which were frequently present were reduced after oxygen. The therapeutic implications of these effects are discussed.