Encapsulated enhanced green fluorescence protein in silica nanoparticle for cellular imaging
Encapsulated enhanced green fluorescence protein in silica nanoparticle for cellular imaging
复制标题
用于细胞成像的二氧化硅纳米颗粒中封装的增强型绿色荧光蛋白
DOI：
10.1039/c0nr00956c
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发表时间：
2011-01-01
期刊：
影响因子：
6.7
通讯作者：
Cao, Aoneng
中科院分区：
文献类型：
--
作者：
Cai, Zhengwei;Ye, Zhangmei;Cao, Aoneng
增强型绿色荧光蛋白（EGFP）通过多个共价键被有效地包裹在二氧化硅纳米颗粒中。二氧化硅包封大大提高了EGFP的荧光强度和对蛋白酶、变性剂和热的稳定性，使其成为潜在的细胞成像荧光探针。
The enhanced green fluorescence protein (EGFP) is efficiently encapsulated in silica nanoparticle by multiple covalent bonds. The silica encapsulation greatly increases EGFP's fluorescence intensity and stabilities against protease, denaturant and heat, making it a potential fluorescence probe for cellular imaging.