Prepubertal testicular tumors: A 20-year experience with 40 cases
Prepubertal testicular tumors: A 20-year experience with 40 cases
复制标题
DOI：
10.1111/j.1442-2042.2010.02629.x
复制
发表时间：
2010-11-01
影响因子：
2.6
通讯作者：
Tanikaze, Saburo
中科院分区：
文献类型：
--
作者：
Hisamatsu, Eiji;Takagi, Shizuko;Tanikaze, Saburo
睾丸肿瘤在儿童中很少见。此外，青春期前睾丸肿瘤(PTT)与青春期后睾丸肿瘤(PTT)有根本的不同。我们回顾了我们20年来40例PTT患者的经验，为PTT患者提供了一种合适的手术方法。所有超声检查怀疑为良性的肿瘤术后均证实为良性。卵黄囊肿瘤和畸胎瘤婴儿术前甲胎蛋白(AFP)水平差异有统计学意义。我们的大多数病例是良性的，最常见的组织病理亚型是畸胎瘤，最近报道。对5例畸胎瘤和3例表皮样囊肿行保留睾丸手术。除1例畸胎瘤患者外，无1例患者在保留睾丸的手术后出现复发或睾丸萎缩。当考虑保留睾丸手术时，我们基于超声检查结果和术前甲胎蛋白水平的算法可能会有所帮助。
Testicular tumors are rare in children. In addition, prepubertal testicular tumors (PTT) are fundamentally different from their postpubertal counterparts. We reviewed our 20-year experience with 40 cases to suggest an algorithm for the appropriate surgical approach for patients with PTT. All tumors ultrasonographically suspected of being benign were confirmed to be benign postoperatively. There was a significant difference between median preoperative alpha-fetoprotein (AFP) levels of infants with yolk sac tumor and teratoma. The majority of our cases were benign, with the most common histopathological subtype being teratoma, as recently reported. Testis-sparing surgery was carried out in five patients with teratoma and three patients with epidermoid cyst. Other than one patient with teratoma, none of the patients developed recurrence or testicular atrophy after testis-sparing surgery. When testis-sparing surgery is considered, our algorithm based on ultrasonographic findings and preoperative AFP levels might be helpful.