Correlation and comparison of magnetic and electric detection of small intestinal electrical activity
Correlation and comparison of magnetic and electric detection of small intestinal electrical activity
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DOI：
10.1152/ajpgi.1997.272.5.g1159
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发表时间：
1997-05-01
影响因子：
4.5
通讯作者：
Richards, WO
中科院分区：
文献类型：
--
作者：
Bradshaw, LA;Allos, SH;Richards, WO
采用浆膜电极和经腹超导量子干涉装置（SQUID）磁强计同时检测麻醉家兔小肠基本电节律（BER）。我们诱导肠系膜缺血，将浆膜电极记录的BER变化与SQUID磁强计相关联。利用傅立叶和自回归技术对数据进行频谱分析，得到误码率。浆膜电极测定的BER频率与SQUID数据测定的BER频率之间存在高度相关（r = 0.96）。此外，在家兔模型上研究了电绝缘体对外加电场和磁场的影响。绝缘体的存在大大衰减了皮肤电极记录的外部电位，但对外部磁场或浆膜电位没有显著影响。我们得出结论，SQUID磁强计可以无创记录小肠BER，这与有创浆膜电极记录的活动高度相关。磁场测量的优点鼓励我们研究临床应用。
The small intestinal basic electrical rhythm (BER) was detected simultaneously with serosal electrodes and a transabdominal superconducting quantum interference device (SQUID) magnetometer in anesthetized rabbits. We induced mesenteric ischemia to correlate serosal electrode recording of changes in BER with the SQUID magnetometer. The BER frequency was obtained by spectral analysis of the data using Fourier and autoregressive techniques. There was a high degree of correlation (r = 0.96) between the BER frequency determined using the serosal electrodes and the BER frequency ascertained from SQUID data. Additionally, the effects of an electrical insulator on the external electric and magnetic fields were studied in the rabbit model. The presence of an insulator profoundly attenuates external electric potentials recorded by cutaneous electrodes but does not significantly affect external magnetic fields or serosal potentials. We conclude that SQUID magnetometers could noninvasively record small intestinal BER that was highly correlated with the activity recorded by invasive serosal electrodes. The advantages of magnetic field measurements have encouraged us to investigate clinical applications.