Functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder
Functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder
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DOI：
10.1176/appi.ajp.159.2.276
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发表时间：
2002-02-01
影响因子：
17.7
通讯作者：
Oldham, JM
中科院分区：
文献类型：
--
作者：
Skodol, AE;Gunderson, JG;Oldham, JM
目的：本研究的目的是比较分裂型、边缘型、回避型或强迫型人格障碍患者与重度抑郁症但无人格障碍患者的心理社会功能。方法：纵向人格障碍协作研究的四个临床中心招募患者（N=668）。通过纵向间隔随访评估基线版本和社会适应量表对经过仔细诊断的研究组进行了一系列心理社会功能领域的比较。结果：发现精神分裂型人格障碍和边缘性人格障碍患者在工作、社会关系和休闲方面比强迫型人格障碍或重度抑郁症患者有明显更多的损害；回避型人格障碍患者处于中间状态。这些差异在各种评估方式中都存在，并且在人口统计学差异和共病轴 I 精神病理学共变后仍然显着。结论：人格障碍是精神疾病发病率的重要来源，与单独的重度抑郁症相比，人格障碍造成更多的功能障碍。
Objective: The purpose of this study was to compare psychosocial functioning in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder and patients with major depressive disorder and no personality disorder.Method: Patients (N=668) were recruited by the four clinical sites of the Collaborative Longitudinal Personality Disorders Study. The carefully diagnosed study groups were compared on an array of domains of psychosocial functioning, as measured by the Longitudinal interval Follow-Up Evaluation-Baseline Version and the Social Adjustment Scale.Results: Patients with schizotypal personality disorder and borderline personality disorder were found to have significantly more impairment at work, in social relationships, and at leisure than patients with obsessive-compulsive personality disorder or major depressive disorder; patients with avoidant personality disorder were intermediate. These differences were found across assessment modalities and remained significant after covarying for demographic differences and comorbid axis I psychopathology.Conclusions: Personality disorders are a significant source of psychiatric morbidity, accounting for more impairment in functioning than major depressive disorder alone.