MR imaging-guided focused ultrasound surgery of uterine leiomyomas: A feasibility study
MR imaging-guided focused ultrasound surgery of uterine leiomyomas: A feasibility study
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DOI：
10.1148/radiol.2271020395
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发表时间：
2003-03-01
期刊：
影响因子：
19.7
通讯作者：
Hynynen, K
中科院分区：
文献类型：
--
作者：
Tempany, CMC;Stewart, EA;Hynynen, K
本文报道了磁共振成像引导下聚焦超声手术治疗子宫平滑肌瘤的可行性和安全性。连续的声波传送到9个目标。温度敏感相位差磁共振成像监测焦点的位置和测量组织温度升高，确保治疗剂量。评估MR图像和子宫切除术标本。6个平滑肌瘤接受了全部治疗剂量，98.5%的超声显像。磁共振测温在所有超声和病例中都是成功的。所有病例mri均可见局灶性坏死灶，其中5例经病理证实。磁共振成像引导聚焦超声引起子宫平滑肌瘤热凝坏死，可行、安全，无严重后果。(c) rsna, 2003。
The feasibility and safety of magnetic resonance (MR) imaging-guided focused ultrasound surgery for uterine leiomyomas is reported. Sequential sonications were delivered to nine targets. Temperature-sensitive phase-difference MR imaging monitored the location of the focus and measured tissue temperature elevations, ensuring therapeutic dose. MR images and hysterectomy specimens were evaluated. Six leiomyomas received full therapeutic doses, and 98.5% of the sonications were visualized. MR thermometry was successful in all sonications and cases. Focal necrotic lesions were seen in all cases at MR, and five were pathologically confirmed. MR imaging-guided focused ultrasound causes thermocoagulation and necrosis in uterine leiomyomas and is feasible and safe, without serious consequences. (C) RSNA, 2003.