Accelerated 1H MRSI using randomly undersampled spiral-based k-space trajectories
Accelerated 1H MRSI using randomly undersampled spiral-based k-space trajectories
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DOI：
10.1002/mrm.25394
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发表时间：
2015-07-01
影响因子：
3.3
通讯作者：
Adalsteinsson, Elfar
中科院分区：
文献类型：
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作者：
Chatnuntawech, Itthi;Gagoski, Borjan;Adalsteinsson, Elfar
目的通过螺旋轨迹欠采样，开发和评估加速磁共振光谱成像（MRSI）的采集和重建方法的性能。理论与方法开发了随机欠采样螺旋采集和灵敏度编码（SENSE）与全变差（TV）正则化，随机SENSE+TV，并在3特斯拉的单排数值模拟、体内单排磁共振成像和体内三维磁共振成像（3D）上进行了评估。比较Random SENSE+TV五种加速MRSI的替代方法。结果在同一采集时间下，与去噪的完全采样和均匀不足采样的SENSE+TV方法相比，随机SENSE+TV方法重建的n-乙酰天冬氨酸（NAA）、肌酸和胆碱图谱的均方根误差（RMSE）分别降低了2.7倍和2倍。对于活体3D-MRSI，随机SENSE+TV的RMSE比均匀SENSE+TV降低了1.6倍。此外，通过随机SENSE+TV，我们在体内单片和3D-MRSI上分别证明了4.5和4的加速因子与完全采样数据的质量相同，分别用重构NAA图的RMSE测量。结论在相同扫描时间下，随机SENSE+TV的代谢物图谱均方根误差低于其他方法。Random SENSE+TV实现高达4.5倍的加速，与完全采样采集的数据质量相当。中华医学杂志，2015,34(4):344 - 344。(c) 2014 Wiley期刊公司
PurposeTo develop and evaluate the performance of an acquisition and reconstruction method for accelerated MR spectroscopic imaging (MRSI) through undersampling of spiral trajectories.Theory and MethodsA randomly undersampled spiral acquisition and sensitivity encoding (SENSE) with total variation (TV) regularization, random SENSE+TV, is developed and evaluated on single-slice numerical phantom, in vivo single-slice MRSI, and in vivo three-dimensional (3D)-MRSI at 3 Tesla. Random SENSE+TV was compared with five alternative methods for accelerated MRSI.ResultsFor the in vivo single-slice MRSI, random SENSE+TV yields up to 2.7 and 2 times reduction in root-mean-square error (RMSE) of reconstructed N-acetyl aspartate (NAA), creatine, and choline maps, compared with the denoised fully sampled and uniformly undersampled SENSE+TV methods with the same acquisition time, respectively. For the in vivo 3D-MRSI, random SENSE+TV yields up to 1.6 times reduction in RMSE, compared with uniform SENSE+TV. Furthermore, by using random SENSE+TV, we have demonstrated on the in vivo single-slice and 3D-MRSI that acceleration factors of 4.5 and 4 are achievable with the same quality as the fully sampled data, as measured by RMSE of reconstructed NAA map, respectively.ConclusionWith the same scan time, random SENSE+TV yields lower RMSEs of metabolite maps than other methods evaluated. Random SENSE+TV achieves up to 4.5-fold acceleration with comparable data quality as the fully sampled acquisition. Magn Reson Med 74:13-24, 2015. (c) 2014 Wiley Periodicals, Inc.