HPV vaccine completion and dose adherence among commercially insured females aged 9 through 26 years in the US

HPV vaccine completion and dose adherence among commercially insured females aged 9 through 26 years in the US
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DOI:
10.1016/j.pvr.2015.10.001
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发表时间:
2016-12-01
影响因子:
3.2
通讯作者:
Du, Ping
Du, Ping
中科院分区:
其他
文献类型:
--
作者:
Liu, Guodong;Kong, Lan;Du, Ping

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背景:尽管自2007年以来,HPV疫苗已被推荐用于女孩和年轻女性,但HPV疫苗在美国的接种率很低。方法:我们使用2008-2011年MarketScan数据进行了一项回顾性队列研究,以检查9-26岁商业保险女性的HPV疫苗接种完成情况和剂量依从性。我们采用多变量logistic回归模型来检验HPV疫苗完成度和HPV疫苗剂量依从性的相关因素。结果:在378,484名9-26岁女性接种HPV疫苗中,只有29.4%完成了HPV疫苗接种。与从初级保健提供者接受疫苗的女性相比,从妇产科提供者接受疫苗的女性更有可能完成疫苗系列。HPV疫苗开始接种的年龄、健康保险计划、季节性模式和流感疫苗接种也与疫苗接种完成显著相关。在111,286名完成HPV疫苗接种的女性中,62.4%在推荐时间表的30天内接种了所有剂量。与HPV疫苗接种完成相关的类似因素始终与HPV疫苗剂量依从性相关。然而,年龄越小(
Background: Although HPV vaccination has been recommended for use in girls and young women since 2007, HPV vaccine uptake is low in the US.Methods: We conducted a retrospective cohort study using the 2008-2011 MarketScan data to examine HPV vaccine completion and dose adherence among commercially insured females aged 9-26 years. We performed multivariable logistic regression models to examine factors related to HPV vaccine completion and HPV vaccine dose adherence.Results: Among 378,484 females aged 9-26 years who initiated HPV vaccination, only 29.4% completed HPV vaccination. Compared with females receiving vaccines from primary care providers, those receiving vaccines from OB/GYN providers were more likely to complete the vaccine series. Age at HPV vaccine initiation, health insurance plan, seasonal pattern, and flu vaccination were also significantly associated with vaccine completion. Among 111,286 females who completed HPV vaccination, 62.4% received all doses within 30 days of the recommended schedules. Similar factors relating to HPV vaccine completion were consistently associated with HPV vaccine dose adherence. However, younger age (