Dosage Adjustments Related to Young or Old Age and Organ Impairment
Dosage Adjustments Related to Young or Old Age and Organ Impairment
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DOI：
10.1002/jcph.816
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发表时间：
2016-12-01
影响因子：
2.9
通讯作者：
Reed, Michael D.
中科院分区：
文献类型：
--
作者：
Burris, James F.;Tortorici, Michael A.;Reed, Michael D.
与年轻或年老和/或器官系统损伤相关的生理学差异改变了许多药物的吸收、分布、代谢和排泄，从而改变了它们的有效性和毒性。本单元讨论了儿科年龄组、老年人和肾脏或肝脏疾病患者所需的药物使用和剂量的常见变化。
Differences in physiology related to young or old age and/or organ system impairment alter the absorption, distribution, metabolism, and excretion of many medications and consequently their effectiveness and toxicity. This module discusses common alterations in medication use and dosage that are required in the pediatric age group, in the elderly, and in patients with renal or hepatic disease.