History of Weight Cycling Is Prospectively Associated With Shorter and Poorer-Quality Sleep and Higher Sleep Apnea Risk in Diverse US Women.
History of Weight Cycling Is Prospectively Associated With Shorter and Poorer-Quality Sleep and Higher Sleep Apnea Risk in Diverse US Women.
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DOI：
10.1097/jcn.0000000000000818
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发表时间：
2021-11-01
期刊：
影响因子：
--
通讯作者：
Aggarwal B
中科院分区：
文献类型：
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作者：
Cao V;Makarem N;Maguire M;Samayoa I;Xi H;Liang C;Aggarwal B
睡眠不良和体重循环史（HWC）与心血管健康状况恶化有关，但有限的研究评估了HWC与睡眠模式不良之间的关系。哥伦比亚大学的美国心脏协会为女性战略重点研究网络队列（n = 506;平均年龄，37 ± 15.7岁; 61%种族/少数民族）用于评估基线时HWC和睡眠的横截面关联以及1年访视时HWC与基线睡眠的前瞻性关联。自我报告体重循环史，定义为至少一次体重减轻和增加10磅或以上（不包括怀孕）。睡眠持续时间、睡眠质量、失眠严重程度和阻塞性睡眠呼吸暂停风险采用经验证的匹兹堡睡眠质量指数、失眠严重程度指数和柏林问卷进行评估。线性和逻辑回归模型，调整年龄，种族/民族，教育，健康保险状况，怀孕史，绝经状态，用于评估HWC与睡眠的关系。大多数女性报告了1次或多次体重循环（72%）。在横断面和前瞻性数据的线性模型中，每增加一次体重循环发作与睡眠持续时间缩短、睡眠质量降低、睡眠起始潜伏期延长、失眠严重程度加重、睡眠障碍增多、睡眠效率降低和睡眠药物使用频率增加有关。在logistic模型中，HWC（≥1 vs 0次发作）与睡眠时间短、睡眠质量差、睡眠起始潜伏期长（≥26分钟）、阻塞性睡眠呼吸暂停风险高和睡眠效率低于85%的可能性更大相关。体重循环的历史可以预测女性睡眠不佳，这表明体重维持可能是促进睡眠健康的重要策略。HWC和睡眠之间的潜在双向关系需要进一步研究。
Poor sleep and history of weight cycling (HWC) are associated with worse cardiovascular health, yet limited research has evaluated the association between HWC and poor sleep patterns. The American Heart Association Go Red for Women Strategically Focused Research Network cohort at Columbia University (n = 506; mean age, 37 ± 15.7 years; 61% racial/ethnic minority) was used to evaluate the cross-sectional associations of HWC and sleep at baseline and the prospective associations of HWC from baseline with sleep at the 1-year visit. History of weight cycling, defined as losing and gaining 10 lb or more at least once (excluding pregnancy), was self-reported. Sleep duration, sleep quality, insomnia severity, and obstructive sleep apnea risk were assessed using the validated Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Berlin questionnaires. Linear and logistic regression models, adjusted for age, race/ethnicity, education, health insurance status, pregnancy history, and menopausal status, were used to evaluate the relation of HWC with sleep. Most women reported 1 or more episodes of weight cycling (72%). In linear models of cross-sectional and prospective data, each additional weight cycling episode was related to shorter sleep duration, poorer sleep quality, longer sleep onset latency, greater insomnia severity, more sleep disturbances, lower sleep efficiency, and higher sleep medication use frequency. In the logistic models, HWC (≥1 vs 0 episodes) was associated with greater odds for short sleep, poor sleep quality, long sleep onset latency (≥26 minutes), high obstructive sleep apnea risk, and sleep efficiency lower than 85%. History of weight cycling predicted poor sleep among women, suggesting that weight maintenance may represent an important strategy to promote sleep health. The potential bidirectional relationship between HWC and sleep requires further investigation.