HLA-DPB1 POLYMORPHISM IN THE THAIS OF SOUTHEAST-ASIA

HLA-DPB1 POLYMORPHISM IN THE THAIS OF SOUTHEAST-ASIA
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DOI:
10.1016/0198-8859(94)90017-5
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发表时间:
1994-05-01
期刊:
影响因子:
2.7
通讯作者:
RUNGRUANG, E
RUNGRUANG, E
中科院分区:
医学4区
文献类型:
--
作者:
CHANDANAYINGYONG, D;STEPHENS, HAF;RUNGRUANG, E

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在这项研究中,我们研究了居住在泰国不同地区和邻近国家的五个泰国民族人群的DPB1等位基因频率。与其他亚洲和太平洋人群,如日本人、中国人、韩国人和巴布亚新几内亚人,DPB1*0501一直被证明是最常见的等位基因相反,东北泰国人和泰国高棉人表现出DPB1*1301的流行。将东南亚泰国人的DPB1等位基因频率与东亚中国人和日本人的已知频率进行比较,似乎证实了先前对这些东方人群之间遗传差异的计算。
In this study we examined DPB1 allele frequencies in five ethnic Thai populations resident in different regions of Thailand and neighboring countries. In contrast to other Asian and Pacific populations such as the Japanese, Chinese, Korean, and Papua New Guineans, where DPB1*0501 has consistently been shown to be the most frequent allele, NE Thais and Thai-Khmers demonstrate a prevalence of DPB1*1301. Comparison of DPB1 allele frequencies in the Thais of SE Asia, with known frequencies in the Chinese and Japanese populations of E Asia, would appear to confirm previous calculations of genetic divergence between these Oriental populations.