Portable coronary active perfusion system for off-pump coronary artery bypass grafting.
Portable coronary active perfusion system for off-pump coronary artery bypass grafting.
复制标题
用于非体外循环冠状动脉旁路移植术的便携式冠状动脉主动灌注系统。
DOI：
10.1016/j.athoracsur.2005.06.064
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
T. Kanamori
中科院分区：
文献类型：
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作者：
Y. Koshida;G. Watanabe;T. Yasuda;S. Tomita;S. Kadoya;T. Kanamori
本研究旨在开发一种用于非体外循环冠状动脉旁路移植术的新灌注系统，并检查即使是简单的冠状动脉灌注系统是否也能在吻合术期间维持足够的血流输送。描述：实验分两个阶段进行。在程序1中，使用3只左前降支闭塞的猪来评估最佳灌注流速和冠状动脉内压，并评估灌注的安全区域。在程序2中，使用6只猪来验证新的便携式冠状动脉灌注系统。说明便携式冠状动脉主动灌注系统中的最佳血流量小于约40 mL/min。（即，便携式冠状动脉主动灌注系统）可以防止冠状动脉闭塞期间的血液动力学恶化和室性心律失常，结论即使是一个简单的泵系统也可以实现安全吻合的有效灌注。需要进一步的研究，以允许该系统的临床使用。
PURPOSEThe present study was performed to develop a new perfusion system for off-pump coronary artery bypass grafting and to examine whether even a simple coronary perfusion system can maintain adequate blood flow delivery during anastomosis. DESCRIPTION: The experiment was performed in two stages. In procedure 1, 3 pigs with left anterior descending artery occlusion were used to evaluate optimal perfusion flow rate and coronary artery internal pressure, and to evaluate the safety area of perfusion. In procedure 2, 6 pigs were used to validate the new portable coronary perfusion system.EVALUATIONThe optimal blood flow in the portable coronary active perfusion system was less than approximately 40 mL/min. The small, easy to use pump system (ie, the portable coronary active perfusion system) may prevent hemodynamic deterioration and ventricular arrhythmia during coronary occlusion, resulting in better maintenance of left ventricular function.CONCLUSIONSEven a simple pump system can achieve effective perfusion for safe anastomosis. Further studies are required to allow the clinical use of this system.