Auditory event-related brain potentials in fibromyalgia syndrome
Auditory event-related brain potentials in fibromyalgia syndrome
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DOI：
10.1007/s00296-004-0443-3
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发表时间：
2005-07-01
影响因子：
4
通讯作者：
Vural, O
中科院分区：
文献类型：
--
作者：
Alanoglu, E;Ulas, UH;Vural, O
目的：本研究的目的是利用听觉事件相关脑电位（ERP）研究纤维肌痛综合征（FMS）患者的认知功能。方法：对36例女性FMS患者和22例正常对照者进行ERP的P300研究。使用SF-36医学结局研究来确定生活质量。记录压痛点数量和病程。认知功能评定采用P300。结果：FMS组与对照组症状差异有统计学意义（P < 0.001）。FMS患者SF-36各亚组评分均显著低于对照组（P < 0.001）。纤维肌痛综合征患者P300潜伏期延长，波幅降低（P < 0.001）。SF-36、压痛点计数、病程和P300各亚组之间无相关性。结论：我们的研究结果表明，FMS影响生活质量和认知能力的功能障碍可以通过脑事件相关电位来确定。
Objective: The aim of this study was to investigate cognitive functions using auditory event-related brain potentials (ERP) in fibromyalgia syndrome (FMS). Methods: The P300 component of ERP was studied in 36 female FMS patients and 22 control subjects. The short form 36 (SF-36) medical outcome study was used to determine quality of life. Number of tender points and disease duration were noted. Cognitive functions were evaluated with P300. Results: The symptoms were discrepant in FMS (P < 0.001). The scores of the eight SF-36 subgroups in FMS patients were significantly lower than in the control group (P < 0.001). Fibromyalgia syndrome patients had prolonged latency and reduced amplitude of P300 (P < 0.001). No correlation was found between the subgroups of SF-36, tender point count, disease duration, and P300. Conclusion: The results of our study reveal that FMS affects quality of life and dysfunction in cognitive abilities can be determined by brain event-related potentials.