Maternal and perinatal outcome in varying degrees of anemia
Maternal and perinatal outcome in varying degrees of anemia
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DOI：
10.1016/s0020-7292(02)00225-4
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发表时间：
2002-11-01
影响因子：
3.8
通讯作者：
Arora, R
中科院分区：
文献类型：
--
作者：
Malhotra, M;Sharma, JB;Arora, R
目的：分析不同程度贫血的母儿结局。研究方法：将447例孕妇分为Ⅰ组（Hb > 11 g%，n = 123）、Ⅱ组（Hb 9-10.9 g%，n = 214）、Ⅲ组（Hb 7-8.9 g%，n = 79）和Ⅳ组（Hb < 7 g%，n = 31）。记录产妇和围产儿结局、分娩方式、产程时间和产后并发症，并采用多元Logistic回归分析，计算产程时间、分娩方式和低出生婴儿的比值比（95%CI）。卡方或Fisher精确检验用于检验比例差异，Student t检验用于检验平均值之间的差异。结果：第IV组的平均年龄（27 +/- 4.25岁）和产次> 3的妇女人数最多。血红蛋白<< 8.9 g% had a 4-6-fold higher risk of prolonged labor compared to Hb >11 g%的患者。异常分娩（剖宫产和阴道手术分娩）的比值比显示，Hb小于或等于7.5 g%的患者的风险高4.8倍（95% CI 1.82，12.7）。平均出生体重在9.6-10.5 g%类别中最大，随着血红蛋白值的增加和减少而下降，在第IV组中最低，第II组中的妇女具有最低的低出生体重和IUGR婴儿数量，没有死产和新生儿死亡，最低的诱导和手术分娩率。结论：轻度贫血在孕产妇和围产儿结局中表现最好。严重贫血与低出生体重儿、引产率、手术分娩和产程延长有关。(C)2002年国际妇产科联合会。由Elsevier Science爱尔兰有限公司出版。保留所有权利。
Objectives: To analyze the maternal and perinatal outcome in varying degrees of anemia. Methods: A total of 447 pregnant women were divided into group I (Hb > 11 g%, n = 123 women), group II (Hb 9-10.9 g%, n = 214 women), group III (Hb 7-8.9 g%, n = 79 women) group IV (Hb < 7 g%, n = 31 women). Their maternal and perinatal outcome, mode of delivery, duration of labor and postpartum complications were noted and analyzed using multiple logistic regression to calculate odds ratios (95% CI) for duration of labor, mode of delivery and low birth babies. Chi square or Fisher's exact test was employed for difference in proportions and Student's t-test for testing difference between means. Results: Mean age (27 +/- 4.25 years) and number of women with parity > 3 were highest in group IV. The patients with Hb < 8.9 g% had a 4-6-fold higher risk of prolonged labor compared to Hb > 11 g%. The odds ratios for abnormal delivery (cesarean and operative vaginal deliveries) showed a 4.8-fold higher risk (95% Cl 1.82, 12.7) in patients with Hb less than or equal to 7.5 g%. The mean birth weight was maximum in the 9.6-10.5 g% category that fell with both increasing and decreasing hemoglobin values, being lowest in Group IV Women in Group II had lowest number of low birth weight and IUGR babies, no stillbirths and neonatal deaths, lowest induction and operative delivery rates. Conclusions: Mild anemia fared best in maternal and perinatal outcome. Severe anemia was associated with increased low birth weight babies, induction rates, operative deliveries and prolonged labor. (C) 2002 International Federation of Gynecology and Obstetrics. Published by Elsevier Science Ireland Ltd. All rights reserved.