Image background removal in comprehensive two-dimensional gas chromatography
Image background removal in comprehensive two-dimensional gas chromatography
复制标题
DOI：
10.1016/s0021-9673(02)01498-x
复制
发表时间：
2003-01-24
影响因子：
4.1
通讯作者：
Ledford, EB
中科院分区：
文献类型：
--
作者：
Reichenbach, SE;Ni, MT;Ledford, EB
本文介绍了一种从全二维气相色谱（GCxGC）产生的数字图像中去除背景水平的新技术。背景去除是更大的定量分析问题中重要的第一步。该方法基于GC X GC数据的结构和统计特性来估计整个色谱图像的背景水平。然后，从图像中减去背景水平，产生色谱图，其中峰高于接近零的平均背景。背景水平去除后，需要进一步分析，以确定样品中峰和化学品之间的定量关系。实验证明，该算法是有效的，在确定和消除GCxGC图像的背景水平。该算法有几个参数控制，并纳入一个交互式程序与图形界面的快速和准确的检测GCxGC峰。(C)2002 Elsevier Science B.V.保留所有权利。
This paper describes a new technique for removing the background level from digital images produced in comprehensive two-dimensional gas chromatography (GCxGC). Background removal is an important first step in the larger problem of quantitative analysis. The approach estimates the background level across the chromatographic image based on structural and statistical properties of GC X GC data. Then, the background level is subtracted from the image, producing a chromatogram in which the peaks rise above a near-zero mean background. After the background level is removed, further analysis is required to determine the quantitative relationship between the peaks and chemicals in the sample. The algorithm is demonstrated experimentally to be effective at determining and removing the background level from GCxGC images. The algorithm has several parametric controls and is incorporated into an interactive program with graphical interface for rapid and accurate detection of GCxGC peaks. (C) 2002 Elsevier Science B.V. All rights reserved.