Signs and Symptoms of First-Onset TMD and Sociodemographic Predictors of Its Development: The OPPERA Prospective Cohort Study
Signs and Symptoms of First-Onset TMD and Sociodemographic Predictors of Its Development: The OPPERA Prospective Cohort Study
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DOI：
10.1016/j.jpain.2013.07.014
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发表时间：
2013-12-01
期刊：
影响因子：
4
通讯作者：
Ohrbach, Richard
中科院分区：
文献类型：
--
作者：
Slade, Gary D.;Bair, Eric;Ohrbach, Richard
尽管颞下颌关节紊乱病 (TMD) 的横断面研究经常报告年轻女性患病率升高，但并未解决其发生的风险。在这里，我们在一项基于社区的美国成年人前瞻性队列研究中评估了 TMD 发病率的社会人口学预测因素。还描述了 TMD 病例的症状和与疼痛相关的残疾。年龄在 18 岁至 44 岁之间、没有 TMD 病史的人在完成有关社会人口学特征的调查问卷后被纳入 4 个研究中心。在中位 2.8 年的随访期内，2,737 名参与者完成了季度筛查问卷。对报告症状的人进行了临床检查，其中 260 人患有首次发作的 TMD。其他调查问卷询问了他们症状的严重程度和影响。单变量和多变量 Cox 回归模型量化了社会人口特征与 TMD 发病率之间的关联。每年有 3.9% 的参与者出现首次 TMD，通常会产生轻度至中度的疼痛和残疾。 TMD 的发病率与年龄呈正相关，而女性的发病率仅略高于男性。与白人相比，亚洲人的 TMD 发病率较低，而非洲裔美国人的发病率较高，尽管后者在调整社会经济环境满意度后有所减弱。 (C) 2013 年，美国疼痛协会
Although cross-sectional studies of temporomandibular disorder (TMD) often report elevated prevalence in young women, they do not address the risk of its development. Here we evaluate sociodemographic predictors of TMD incidence in a community-based prospective cohort study of U.S. adults. Symptoms and pain-related disability in TMD cases are also described. People aged 18 to 44 years with no history of TMD were enrolled at 4 study sites when they completed questionnaires about sociodemographic characteristics. During the median 2.8-year follow-up period, 2,737 participants completed quarterly screening questionnaires. Those reporting symptoms were examined clinically and 260 had first-onset TMD. Additional questionnaires asked about severity and impact of their symptoms. Univariate and multivariable Cox regression models quantified associations between sociodemographic characteristics and TMD incidence. First-onset TMD developed in 3.9% of participants per annum, typically producing mild to moderate levels of pain and disability in cases. TMD incidence was positively associated with age, whereas females had only slightly greater incidence than males. Compared to whites, Asians had lower TMD incidence whereas African Americans had greater incidence, although the latter was attenuated somewhat after adjusting for satisfaction with socioeconomic circumstances. (C) 2013 by the American Pain Society