Evaluation of Cervical Cancer Screening Programs in Cote d'Ivoire, Guyana, and Tanzania: Effect of HIV Status
Evaluation of Cervical Cancer Screening Programs in Cote d'Ivoire, Guyana, and Tanzania: Effect of HIV Status
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DOI：
10.1371/journal.pone.0139242
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发表时间：
2015-09-25
期刊：
影响因子：
3.7
通讯作者：
Lu, Enriquito
中科院分区：
文献类型：
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作者：
Anderson, Jean;Wysong, Megan;Lu, Enriquito
艾滋病毒感染增加了妇女患宫颈癌的风险，在艾滋病毒流行率高和筛查资源有限的国家，宫颈癌发病率和死亡率更高。醋酸目视检查（VIA）可以在单次就诊方法（SVA）中筛查和治疗宫颈病变，但其在艾滋病毒感染妇女中的表现数据有限。本研究的目的是在为感染艾滋病毒的妇女服务的项目中检查使用VIA/SVA的宫颈癌筛查。方法2009 - 2012年在科特迪瓦、圭亚那和坦桑尼亚实施VIA/SVA项目，对VIA阳性病变进行冷冻治疗。采用横断面研究设计，采用卡方检验进行比较，并构建多变量logistic回归模型，检查HIV状态对VIA阳性和适合冷冻治疗的病变的影响。的p值
BackgroundHIV infection increases a woman's risk for cervical cancer, and cervical cancer incidence and mortality rates are higher in countries with high HIV prevalence and limited resources for screening. Visual inspection with acetic acid (VIA) allows screening and treatment of cervical lesions in a single-visit approach (SVA), but data on its performance in HIV-infected women are limited. This study's objective was to examine cervical cancer screening using VIA/SVA in programs serving HIV-infected women.MethodsA VIA/SVA program with cryotherapy for VIA-positive lesions was implemented in Cote d'Ivoire, Guyana, and Tanzania from 2009 to 2012. The effect of HIV status on VIA positivity and on presence of cryotherapy-eligible lesions was examined using a cross-sectional study design, with Chi-square tests for comparisons and constructed multivariate logistic regression models. A P-value of