Emergence and phylogenetic analysis of a novel Seneca Valley virus strain in the Guangxi Province of China
Emergence and phylogenetic analysis of a novel Seneca Valley virus strain in the Guangxi Province of China
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DOI：
10.1016/j.rvsc.2020.03.020
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发表时间：
2020-06-01
影响因子：
2.4
通讯作者：
Wei, Zuzhang
中科院分区：
文献类型：
--
作者：
Wang, Hao;Niu, Chenxia;Wei, Zuzhang
塞内卡病毒A (SVA)，也称为塞内卡谷病毒(SVV)，是一种新出现的传染性病原体，已在巴西、美国、哥伦比亚、泰国、加拿大和中国一些省份的猪群中检测到，表明这种新型病毒的地理分布日益扩大。在此，我们分离并鉴定了一种 SVV，命名为 SVA CH-GX-01-2018，该病毒被认为是 2018 年 8 月中国广西省猪群育肥猪口鼻和蹄部典型水疱性病变的原因。系统发育分析和序列比对表明，该 SVA CH-GX-01-2018 菌株与 2017 年在广东省分离的菌株密切相关。与中国南方邻近省份广西的基因组核苷酸水平有98.6%的一致性。我们的研究结果描述了华南猪群中的一种新型 SVV 感染，并强调了监测、加强生物安全措施和开发疫苗以防止这种病毒病原体传播的重要性。
Senecavirus A (SVA), also known as Seneca Valley virus (SVV), is an emerging infectious pathogen which have been detected in swine herds from the Brazil, USA, Colombia, Thailand, Canada and some provinces in China, suggesting an increasing geographic distribution of this novel virus. Here, we isolated and characterized a SVV, designated SVA CH-GX-01-2018, thought to be responsible for typical vesicular lesions on the snouts and hooves of finishing pigs from a swine herds in Guangxi province, China, in August 2018. Phylogenetic analysis and sequence alignment indicated that this SVA CH-GX-01-2018 strain was closely related to the strains isolated in 2017 in Guangdong province, a neighboring province of Guangxi, South China, with 98.6% identity at the genome nucleotide level. Our findings characterized a novel SVV infection in pigs from South China and emphasize the importance of surveillance, reinforcing biosecurity measures and developing vaccines to prevent the spread of this viral pathogen.