ESOPHAGEAL-CARCINOMA METASTATIC TO THE STOMACH - A CLINICOPATHOLOGIC STUDY OF 35 CASES
ESOPHAGEAL-CARCINOMA METASTATIC TO THE STOMACH - A CLINICOPATHOLOGIC STUDY OF 35 CASES
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DOI：
10.1002/1097-0142(19851101)56:9
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发表时间：
1985-01-01
期刊：
影响因子：
6.2
通讯作者：
WATANABE, H
中科院分区：
文献类型：
--
作者：
SAITO, T;IIZUKA, T;WATANABE, H
本文分析了35例食管癌胃转移的临床资料。其中10例是在手术标本中发现的，25例是在尸检中发现的。所有患者均为男性，平均年龄62岁。原发病灶多位于胸段食管中部，直径大于7cm。未分化癌占29%。34%的原发病灶局部扩散到邻近结构。主要表现为淋巴管浸润、食管壁内转移和淋巴结转移。胃内转移灶多位于贲门部，大小小于2 cm或大于4 cm，并可重新定位于肌下肿瘤。胃转移瘤偶尔从粘膜下层扩散到邻近结构。尽管积极的治疗，预后极差，因为癌的多个扩散到局部区域，淋巴结和远处器官。本文讨论了本病的临床病理特点及可能的治疗方法。
Esophageal carcinoma metastatic to the stomach was analyzed in 35 patients. Ten were discovered in surgical specimens and 25 at autopsy. All patients were men with a mean age of 62 years. Primary lesions were most frequently located in the middle of thoracic esophagus and were larger than 7 cm. Undifferentiated carcinoma was found in 29% of the patients. Local spread of the primary lesions to neighboring structures was seen in 34%. Lymphatic invasion, and intramural metastases within the esophagus, as well as lymph node metastases, were predominant. Metastatic lesions within the stomach were mostly located in the gastric cardia, were less than 2 cm or more than 4 cm in size, and reasembled submuscosal tumors. Gastric metastases occasionally spread from the submucosa to neighboring structures. In spite of aggressive treatment, the prognosis was extremely poor because of multiple spread of carcinoma to local regions, lymph nodes, and distant organs. The clinicopathologic characteristics of this disease and possible treatment are discussed.