Quantitative Evaluation of Half-Cone-Beam Scan Paths in Triple-Camera Brain SPECT.
Quantitative Evaluation of Half-Cone-Beam Scan Paths in Triple-Camera Brain SPECT.
复制标题
三相机脑 SPECT 中半锥束扫描路径的定量评估。
DOI：
10.1109/tns.2008.2003255
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发表时间：
2008
影响因子：
1.8
通讯作者：
Metzler,ScottD
中科院分区：
文献类型：
--
作者：
Ter-Antonyan,Ruben;Jaszczak,RonaldJ;Bowsher,JamesE;Greer,KimL;Metzler,ScottD
在与人脑SPECT成像相关的研究中，模拟了半锥束(HCB)在不同扫描路径下的准直，并与模拟的扇束和平行孔圆形轨道采集的盘状体模投影数据进行了比较。根据重建图像的光子探测效率、均方根误差、对比度和信噪比测量，对采集类型进行定量评估。我们证明，采用半锥形光束准直器和圆螺旋扫描路径的三相机SPECT系统，在相同的空间分辨率下，效率比扇束提高26%，比平行孔准直器提高128%，并且在重建的盘状体模图像中不显示可见的轴向采样伪影。此外，我们使用Hoffman 3D脑模型对三重HCB环和螺旋获取进行了定性的实验评估。重建的脑模图像由于降低了噪声和没有明显的采样伪影而显示出更高的质量。与传统的扇束和平行孔SPECT相比，三重HCB环形和螺旋SPECT具有改善脑成像的潜力，与传统的扇束和平行孔SPECT相比，由于提高了同等空间分辨率的效率，因此可以产生更高的图像质量，重建误差更小，病变可检出性更好。
In this study related to human brain SPECT imaging, simulation of half-cone-beam (HCB) collimation with different scan paths is performed and compared with simulated fan-beam and parallel-hole circular orbit acquisitions of disk-phantom projection data. Acquisition types are quantitatively evaluated based on the photon detection efficiency, the root-mean-squared error, contrast and signal-to-noise ratio measurements of the reconstructed images. We demonstrate that a triple-camera SPECT system with half-cone-beam collimators and circle-and-helix scan paths can offer up to a 26% efficiency increase over fan-beam, and up to a 128% increase over parallel-hole collimators for equal spatial resolutions, and display no visible axial sampling artifacts in reconstructed disk-phantom images. In addition, we perform qualitative experimental evaluation of triple-HCB circle-and-helix acquisition using a Hoffman 3D brain phantom. Reconstructed brain phantom images show improved quality due to reduced noise and no apparent sampling artifacts. Triple-HCB circle-and-helix SPECT has a potential for improved brain imaging, producing higher image quality with a smaller reconstruction error and better lesion detectability due to increased efficiency for equal spatial resolution compared to conventional fan-beam and parallel-hole SPECT.