Palatogenesis and cutaneous repair: A two-headed coin.
Palatogenesis and cutaneous repair: A two-headed coin.
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DOI：
10.1002/dvdy.24224
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发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Dunnwald M
中科院分区：
文献类型：
--
作者：
Biggs LC;Goudy SL;Dunnwald M
产后皮肤损伤后的修复机制是一种基本的生存功能，需要一系列精心安排的分子和细胞事件。最终，人体将通过细胞增殖、迁移、分化和融合等过程关闭这个洞。这些过程与胚胎发生和组织形态发生过程相似。腭突形成是由两个独立的腭架形成的，彼此朝向对方生长并融合，直觉上与两个迁移的上皮额的皮肤伤口闭合有许多相似之处。本文就皮肤发育、伤口愈合、腭裂发生和口面部裂隙的研究现状进行综述，认为口面部裂隙和伤口愈合是两个保守的过程，具有共同的通路和基因调控网络。
The reparative mechanism that operates following post-natal cutaneous injury is a fundamental survival function that requires a well-orchestrated series of molecular and cellular events. At the end, the body will have closed the hole using processes like cellular proliferation, migration, differentiation and fusion. These processes are similar to those occurring during embryogenesis and tissue morphogenesis. Palatogenesis, the formation of the palate from two independent palatal shelves growing towards each other and fusing, intuitively, shares many similarities with the closure of a cutaneous wound from the two migrating epithelial fronts. In this review, we summarize the current information on cutaneous development, wound healing, palatogenesis and orofacial clefting and propose that orofacial clefting and wound healing are conserved processes that share common pathways and gene regulatory networks.
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影响因子：
1.2
作者：
Bush, JO;Maltby, KM;Jiang, RL
通讯作者：
Jiang, RL
影响因子：
5.3
作者：
Beaty, T. H.;Taub, M. A.;Scott, A. F.;Murray, J. C.;Marazita, M. L.;Schwender, H.;Parker, M. M.;Hetmanski, J. B.;Balakrishnan, P.;Mansilla, M. A.;Mangold, E.;Ludwig, K. U.;Noethen, M. M.;Rubini, M.;Elcioglu, N.;Ruczinski, I.
通讯作者：
Ruczinski, I.
DOI：
10.1002/ajmg.10778
发表时间：
2002-10-15
期刊：
AMERICAN JOURNAL OF MEDICAL GENETICS
影响因子：
--
作者：
Brunner, HG;Hamel, BCJ;van Bokhoven, H
通讯作者：
van Bokhoven, H
影响因子：
5.2
作者：
Amini-Nik, Saeid;Glancy, Dylan;Alman, Benjamin A.
通讯作者：
Alman, Benjamin A.
影响因子：
15.9
作者：
Amini-Nik, Saeid;Cambridge, Elizabeth;Alman, Benjamin A.
通讯作者：
Alman, Benjamin A.