Electrokinetic transport through rough microchannels
Electrokinetic transport through rough microchannels
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DOI：
10.1021/ac0347157
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发表时间：
2003-11-01
影响因子：
7.4
通讯作者：
Li, DQ
中科院分区：
文献类型：
--
作者：
Hu, YD;Werner, C;Li, DQ
由于微加工技术或颗粒粘附，大多数微流体装置中存在表面粗糙度。这是非常可取的，以了解粗糙度对微尺度传输过程的影响。在这项研究中，我们开发了一个三维，有限体积为基础的数值模型来模拟电渗输运的微通道与矩形棱柱粗糙元件的表面。各种配置的粗糙度进行了研究，结果表明，由于粗糙度引起的局部压力场和电渗滑移边界速度的变化对液体输送的均匀化效果的不同程度。分析了通过粗糙微通道的3D样品传输。结果表明，在电场作用下，样品在粗糙元件之间的通道中的输运速度要快得多;在高度和宽度方向上的浓度场是不均匀的。研究了电动性质对液体流动和样品传输的影响。结果表明，电渗透迁移率的增加或电泳迁移率的降低可以显着提高浓度场的均匀性。
Surface roughness is present in most microfluidic devices as a result of the microfabrication techniques or particle adhesion. It is highly desirable to understand the roughness effect on microscale transport processes. In this study, we developed a 3-D, finite-volume-based numerical model to simulate electroosmotic transport in microchannels with rectangular prism rough elements on the surfaces. Various configurations of roughness were investigated, and the results show different degrees of an even-out effect on liquid transport due to the roughness-induced local pressure field and the variation of the electroosmotic slip boundary velocities. 3D-sample transport through rough microchannels was analyzed. The results demonstrate that the sample's transport under the electrical field is much faster in the pathway between the rough elements; the concentration field in the height and width direction is not uniform. The influence of the electrokinetic properties on liquid flow and sample transport was studied. It was found that the increase of the electroosmotic mobility or the decrease of the electrophoretic mobility can dramatically enhance the uniformity of the concentration field.