INACTIVATION BY BROMINE OF SINGLE POLIOVIRUS PARTICLES IN WATER
INACTIVATION BY BROMINE OF SINGLE POLIOVIRUS PARTICLES IN WATER
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DOI：
10.1128/aem.31.2.298-303.1976
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发表时间：
1976-01-01
影响因子：
4.4
通讯作者：
SHARP, DG
中科院分区：
文献类型：
--
作者：
FLOYD, R;JOHNSON, JD;SHARP, DG
定量电子显微镜显示，氟利昂提取的脊髓灰质炎病毒在蔗糖梯度中呈速度带状，含有超过 95% 的单颗粒。这种分散良好的病毒在湍流水中与 Br 快速反应，在 pH 7、2°C 的条件下，在 10 秒内以 1 log10 单位的速度损失噬菌斑滴度。 C，并且Br浓度为2.2μM。 10 和 20 度时。 C 消毒速率（log10 噬菌斑形成单位/秒）更快，并且在两种温度下，随着 Br 浓度的增加，消毒速率以近似线性的方式增加。 2.度。 C 没有观察到这种线性关系。
Quantitative electron microscopy shows that Freon-extracted poliovirus, velocity banded in a sucrose gradient, contains over 95% single particles. This well-dispersed virus reacts rapidly with Br in turbulent flowing water, losing plaque titer at the rate of 1 log10 unit in 10 s at pH 7, 2.degree. C, and at a Br concentration of 2.2 .mu.M. At 10 and 20.degree. C the rate of disinfection (log10 plaque-forming units/s) is faster, and at both temperatures it increases in approximately linear fashion with increasing Br concentration. At 2.degree. C such a linear relationship is not observed.