Management of respiratory motion in PET/computed tomography: the state of the art.
Management of respiratory motion in PET/computed tomography: the state of the art.
复制标题
DOI：
10.1097/mnm.0000000000000048
复制
发表时间：
2014-02
影响因子：
1.5
通讯作者：
Meyer ME
中科院分区：
文献类型：
--
作者：
Pépin A;Daouk J;Bailly P;Hapdey S;Meyer ME
联合PET/计算机断层扫描（CT）在癌症诊断、随访和治疗计划中具有价值。对于位于胸部或腹部的癌症，患者的呼吸会导致PET和CT图像中的伪影和错误。已经开发了许多不同的伪影避免或校正方法;大多数方法基于呼吸信号和PET采集之间的门控采集和同步。呼吸信号通常由跟踪与患者呼吸相关的生理特征的外部传感器产生。呼吸门控是一种补偿技术，其中使用时间或幅度合并来排除重建PET图像中的运动。尽管该技术在常规临床实践中进行，但它无法充分校正呼吸运动，因为每个门可以混合几个组织位置。研究人员建议从门控采集中选择PET事件或执行多个PET采集（对应于屏气CT位置）。然而，如果要在合并后在不同门中获得足够的计数统计，则必须增加PET采集时间。因此，其他研究人员已经评估了考虑所有计数统计（不增加采集持续时间）并在重建过程之前、期间或之后整合运动信息的校正技术。在这里，我们提供了一个概述运动是如何管理，以克服PET/CT图像中的呼吸运动。
Combined PET/computed tomography (CT) is of value in cancer diagnosis, follow-up, and treatment planning. For cancers located in the thorax or abdomen, the patient’s breathing causes artifacts and errors in PET and CT images. Many different approaches for artifact avoidance or correction have been developed; most are based on gated acquisition and synchronization between the respiratory signal and PET acquisition. The respiratory signal is usually produced by an external sensor that tracks a physiological characteristic related to the patient’s breathing. Respiratory gating is a compensation technique in which time or amplitude binning is used to exclude the motion in reconstructed PET images. Although this technique is performed in routine clinical practice, it fails to adequately correct for respiratory motion because each gate can mix several tissue positions. Researchers have suggested either selecting PET events from gated acquisitions or performing several PET acquisitions (corresponding to a breath-hold CT position). However, the PET acquisition time must be increased if adequate counting statistics are to be obtained in the different gates after binning. Hence, other researchers have assessed correction techniques that take account of all the counting statistics (without increasing the acquisition duration) and integrate motion information before, during, or after the reconstruction process. Here, we provide an overview of how motion is managed to overcome respiratory motion in PET/CT images.