Residential magnetic field exposure and childhood brain cancer - A meta-analysis
Residential magnetic field exposure and childhood brain cancer - A meta-analysis
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DOI：
10.1097/ede.0b013e3181690715
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发表时间：
2008-05-01
期刊：
影响因子：
5.4
通讯作者：
Kheifets, Leeka
中科院分区：
文献类型：
--
作者：
Mezei, Gabor;Gadallah, May;Kheifets, Leeka
背景资料：我们对磁场暴露和儿童脑肿瘤的研究进行了荟萃分析，以评估结果的同质性，检查异质性的原因，并得出一个汇总效应估计。比较儿童脑癌和儿童白血病的研究结果也可能有助于评估儿童白血病研究中的选择偏倚的潜力。使用逆方差加权法，分别计算距离、导线代码以及测量和计算的磁场的汇总效应估计值。进行敏感性分析，以评估个别研究的影响，潜在的选择偏差，和出版bias.Results的可能性：与线代码的研究除外，结果是兼容的跨研究的同质性。距离的总体优势比（95%置信区间）为0.88（0.57-1.37
Background: We conducted a meta-analysis of studies on magnetic field exposure and childhood brain tumors to evaluate homogeneity in the results, to examine reasons for heterogeneity, and to derive a summary effect estimate. Comparison of results from studies of childhood brain cancer and childhood leukemia may also help to assess the potential for selection bias in childhood leukemia studies.Methods: We included results from 13 studies. Using an inverse variance-weighted method, summary effect estimates were calculated separately for distance, wire codes, and measured and calculated magnetic fields. Sensitivity analyses were conducted to assess the influence of individual studies, the potential for selection bias, and the possibility of publication bias.Results: With the exception of wire-code studies, results were compatible with homogeneity across studies. The summary odds ratios (95% confidence intervals) were 0.88 (0.57-1.37) for distance