Are peri-implantitis lesions different from periodontitis lesions?
Are peri-implantitis lesions different from periodontitis lesions?
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DOI：
10.1111/j.1600-051x.2010.01672.x
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发表时间：
2011-03-01
影响因子：
6.7
通讯作者：
Donati, Mauro
中科院分区：
文献类型：
--
作者：
Berglundh, Tord;Zitzmann, Nicola U.;Donati, Mauro
目的比较种植体周围炎和牙周炎病变的组织病理学特征。进行人体活检材料和动物实验的研究considered.ResultsWhile全面的信息存在关于人类牙周炎病变的组织病理学特征，很少有研究评估种植体周围病变在人体活检材料。在10项研究中评价了实验性种植体周围炎病变，其中3项研究包括与实验性牙周炎的比较。人体活检材料：炎性细胞浸润（ICT）的顶端延伸在种植体周围炎中比在牙周炎中更明显，并且在大多数情况下位于囊袋上皮的顶端。浆细胞和淋巴细胞占主导地位的细胞在两种类型的病变，而中性粒细胞和巨噬细胞发生在种植体周围炎的比例较大。实验研究：结扎线的放置与牙菌斑的形成一起导致支持组织和种植体和牙齿周围的大ICT的损失。结扎去除后，一个“自限性”的过程中发生在牙齿周围的组织与结缔组织囊分开的ICT从骨，而在种植体周围组织的ICT延伸到骨crimin.ConclusionDespite相似的临床特征和病因学的种植体周围炎和牙周炎，关键的组织病理学差异存在于两个病变之间。
P>AimTo compare histopathological characteristics of peri-implantitis and periodontitis lesions.MethodsA search was conducted on publications up to July 2010. Studies carried out on human biopsy material and animal experiments were considered.ResultsWhile comprehensive information exists regarding histopathological characteristics of human periodontitis lesions, few studies evaluated peri-implantitis lesions in human biopsy material. Experimental peri-implantitis lesions were evaluated in 10 studies and three of the studies included comparisons to experimental periodontitis. Human biopsy material: the apical extension of the inflammatory cell infiltrate (ICT) was more pronounced in peri-implantitis than in periodontitis and was in most cases located apical of the pocket epithelium. Plasma cells and lymphocytes dominated among cells in both types of lesions, whereas neutrophil granulocytes and macrophages occurred in larger proportions in peri-implantitis. Experimental studies: placement of ligatures together with plaque formation resulted in loss of supporting tissues and large ICTs around implants and teeth. Following ligature removal, a "self-limiting" process occurred in the tissues around teeth with a connective tissue capsule that separated the ICT from bone, while in peri-implant tissues the ICT extended to the bone crest.ConclusionDespite similarities regarding clinical features and aetiology of peri-implantitis and periodontitis, critical histopathological differences exist between the two lesions.