Neuroimaging
Neuroimaging
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DOI：
10.1111/j.1750-3639.1997.tb00978.x
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发表时间：
1997-10
期刊：
影响因子：
6.4
通讯作者：
中科院分区：
文献类型：
--
作者：
表观弥散系数（ADC）成像是检测脑水肿的敏感方法。我们观察了细胞毒性型和血管源性脑水肿的超声定位及局部组织含水量与ADC值的相关性。梅霍德在麻醉和生理参数监测下，对成人csu进行大脑中动脉闭塞或皮层冷损伤。观察ADC值、血脑屏障（BBB）改变、局部组织水流量及组织学改变。结果在早期缺血的细胞毒性水肿。灰、白色物质的ADC值随含水量的增加而降低。相关线显示不同的斜率和截距。减少与星形胶质细胞和少突胶质细胞肿胀有关。冷损伤后血管源性水肿。ADC值随组织含水量的增加而增加。白色物质纤维间隙的扩大与ADC值的增加相关。评论. ADC值是研究脑水肿病理生理的有力工具。水肿液的不同定位可能解释了不同类型水肿之间ADC的不同行为。W1.4.03 MRI上的白色高信号：两例皮质基底节变性病例的神经病理学研究Doi，T.l，Okino，S1，Tatamori，M.！，Makifuchi，T.2“日本金泽大学医学部神经内科ZNational Saigata医院神经病理科
Apparent diffusion corfficient (ADC) imaging is a sensitive method to detect brain edema. We examined the ultrasmctural localization of edema fluid and the correlation of regional tissue water content to ADC \ d u e in cytotoxic type of and vasogenic type of brain edema. Merhodr. Adult csu were subjected to either middle cerebral artery occlusion or cortical cold lesion under anesthesia and monitohng of physiologic parameters. an0 ADC changes, blood-brain barrier (BBB) changes, regional tissue water conrent and histolou were examined. Results. In cytotoxic edema at early ischemia. ADC decreased in parallel to the incrrase of water content in both gray and white matter. The correlation lines showed different slopes and intercepts. The decrease was ccrrelated with the swelling of astrocytes and oligodcndroglia. In vasogenic edema after cold lesion. ADC increased in parallel to the increase of tissue water content. Enlargement of inter-fiber space of the white matter was correlated with the increase of ADC. Comments. ADC is a powerful tool for the research of brain edema pathophysiology. The observed different localization of edema fluid may explain the different behavior of ADC among different types of edema. W1.4.03 White matter hyperintensities on MRI: neuropathological study of two cases with corticobasal degeneration Doi, T.l, Okino, S1, Tatamori, M.!, Makifuchi, T.2 ‘Department of Neurology, Kanazawa University School of Medicine ZDepartment of Neuropathology, National Saigata Hospital, Japan