A micromagnetic actuator for biomolecule manipulation
A micromagnetic actuator for biomolecule manipulation
复制标题
用于生物分子操纵的微磁致动器
DOI：
10.1016/j.sna.2006.08.012
复制
发表时间：
2007
影响因子：
4.6
通讯作者：
P. Galvin
中科院分区：
文献类型：
--
作者：
H. Rostaing;H. Chetouani;M. Gheorghe;P. Galvin
报道了一种有效且低成本的吸引和混合磁珠的方法，其中微蛇形线形状与永磁体结合使用以使磁珠磁性饱和。该研究包括设计，建模和一种新的装置的操作顺磁珠的经验评价。报告的结果表明，该设备的性能与建模的预期一致，并表明该设备具有显着的应用潜力，需要在BioMEMS内操作生物分子，如分离和纯化核酸和蛋白质。
An efficient and low cost way to attract and mix magnetic beads is reported, in which microserpentines wires shape were used in combination with a permanent magnet to polarize and magnetically saturate beads. The research included the design, modelling and an empirical evaluation of a novel device for manipulation of paramagnetic beads. The results reported indicate that the performance of this device agrees with expectations from the modelling, and suggests that the device has significant potential for applications requiring manipulation of biomolecules within BioMEMS, such isolation and purification of nucleic acids and proteins.