Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor
Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor
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以 1,4-二恶烷为供氢体的铱催化烯烃选择性转移氢化
DOI：
10.1021/acs.orglett.9b01989
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发表时间：
2019
期刊：
影响因子：
5.2
通讯作者：
Sawamura Masaya
中科院分区：
文献类型：
--
作者：
Zhang Deliang;Iwai Tomohiro;Sawamura Masaya
以铱为催化剂，1，4-二氧六环为氢供体，研究了烯烃的转移氢化反应。使用1，2-双（二环己基膦基）乙烷（DCyPE），具有庞大的和高度供电子的性质，导致高的催化活性。聚苯乙烯交联的双膦PS-DPPBz制备了可重复使用的多相催化剂。这些均相和非均相方案实现了烯烃在相同分子中的其他潜在可还原官能团如羰基、硝基、氰基和亚氨基上的化学选择性转移氢化。
The iridium-catalyzed transfer hydrogenation of alkenes using 1,4-dioxane as a hydrogen donor is described. The use of 1,2-bis(dicyclohexylphosphino)ethane (DCyPE), featuring bulky and highly electron-donating properties, led to high catalytic activity. A polystyrene-cross-linking bisphosphine PS-DPPBz produced a reusable heterogeneous catalyst. These homogeneous and heterogeneous protocols achieved chemoselective transfer hydrogenation of alkenes over other potentially reducible functional groups such as carbonyl, nitro, cyano, and imino groups in the same molecule.