Methoxylation pathway in biodesulfurization of model organosulfur compounds with Mycobacterium sp.
Methoxylation pathway in biodesulfurization of model organosulfur compounds with Mycobacterium sp.
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DOI：
10.1016/j.biortech.2008.10.010
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发表时间：
2009-03-01
影响因子：
11.4
通讯作者：
Li, Wei
中科院分区：
文献类型：
--
作者：
Chen, Han;Cai, Yu-Bei;Li, Wei
用于模型有机硫化合物例如，二苯并噻吩（DBT）。该途径被定义为扩展的4S途径，其结合了传统的4S途径和从2-羟基联苯（HBP）到2-甲氧基联苯（2-MBP）的甲氧基化途径。通过气相色谱-质谱（GC-MS）分析证实了2-MBP的形成。在4，6-二甲基二苯并噻吩（4，6-DMDBT）的脱硫中也获得了类似的途径，证实了分枝杆菌菌株在脱硫过程中的甲氧基化反应。与2-HBP相比。2-MBP对细胞生长和脱硫活性的抑制作用较小。因此，从2-HBP到2-MBP的甲氧基化途径对微生物的抑制作用较小。以2-MBP为最终产物的新途径可能是化石燃料进一步脱硫的替代途径。(c)2008爱思唯尔有限公司保留所有权利。
A metabolic pathway for the biodesulfurization of model organosulfur compounds e.g., dibenzothiophene (DBT), is proposed. This pathway, defined as extended 4S pathway, incorporates the traditional 4S pathway with the methoxylation pathway from 2-hydroxybiphenyl (HBP) to 2-methoxybiphenyl (2-MBP). The formation of 2-MBP was confirmed by the gas chromatography-mass spectrometry (GC-MS) analysis. A similar pathway was also obtained in the desulfurization of 4,6-dimethyldibenzothiophene (4,6-DMDBT), confirming the methoxylation reaction in the desulfurization process by the Mycobacterium sp. strain. Compared with 2-HBP. 2-MBP has much slighter inhibition effect on the cell growth and desulfurization activity. Thus, the methoxylation pathway from 2-HBP to 2-MBP would make less inhibitory effect on the microbe. The new pathway with 2-MBP as the end product may be an alternative for the further desulfuration of the fossil fuels. (c) 2008 Elsevier Ltd. All rights reserved.