Respiratory syncytial virus is an important cause of community-acquired lower respiratory infection among hospitalized adults
Respiratory syncytial virus is an important cause of community-acquired lower respiratory infection among hospitalized adults
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DOI：
10.1093/infdis/174.3.456
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发表时间：
1996-09-01
影响因子：
6.4
通讯作者：
Breiman, RF
中科院分区：
文献类型：
--
作者：
Dowell, SF;Anderson, LJ;Breiman, RF
呼吸道合胞病毒（RSV）是婴幼儿下呼吸道疾病的最重要原因，但很少被认为是成人社区获得性下呼吸道感染的原因之一。 1990 年 12 月至 1992 年 5 月期间，对俄亥俄州两个县因社区获得性肺炎住院的所有非住院成人进行了评估。RSV 季节期间入院的 1195 名成人中，有 53 名 (4.4%) 和淡季 390 名成人中的 4 名 (1.0%) 有 RSV 感染的血清学证据，这使得 RSV 成为确定的四种最常见病原体之一，RSV 感染患者 临床特征（例如，喘息和干啰音）将他们与所有非 RSV 感染患者区分开来，其他特征（例如，白细胞计数未升高）将他们与细菌或非典型病原体感染者区分开来。然而，57 名 RSV 感染患者在住院期间均未诊断出 RSV 感染。对于 11 月至 4 月期间住院的社区获得性下呼吸道感染成人，鉴别诊断时应考虑 RSV。
Respiratory syncytial virus (RSV), the most important cause of lower respiratory disease in infants and young children, is rarely considered among the causes for community-acquired lower respiratory infection in adults. All noninstitutionalized adults hospitalized with community-acquired pneumonia in two Ohio counties were evaluated between December 1990 and May 1992. Fifty-three (4.4%) of 1195 adults admitted during the RSV seasons and 4 (1.0%) of 390 in the off-season had serologic evidence of RSV infection, making RSV one of the four most common pathogens identified, RSV-infected patients had clinical features (e.g., wheezing and rhonchi) that distinguished them from all non-RSV-infected patients and other features (e.g., nonelevated white blood cell counts) that distinguished them from those infected with bacterial or atypical agents, However, RSV infection was not diagnosed during hospitalization for any of the 57 RSV-infected patients. RSV should be considered in the differential diagnosis for adults hospitalized between November and April with community-acquired lower respiratory infection.