Brain areas selective for both observed and executed movements
Brain areas selective for both observed and executed movements
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DOI：
10.1152/jn.00238.2007
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发表时间：
2007-09-01
影响因子：
2.5
通讯作者：
Heeger, David J.
中科院分区：
文献类型：
--
作者：
Dinstein, Ilan;Hasson, Uri;Heeger, David J.
当观察到一个特定的运动时，视觉和视觉运动神经元的一个子集在观察者的大脑中是活跃的，形成了观察到的运动的表征。类似地，当执行动作时，选择动作的运动神经元和视觉运动神经元的子集被激活，形成执行的动作的表征。在这项研究中，我们使用功能磁共振成像适应方案来评估皮层对同时观察到的和执行的运动的反应选择性。受试者自由地与录制下来的对手玩石头-布-剪刀游戏，有时在随后的试验中重复观察或执行相同的动作。在重复观察或重复执行同一动作的过程中，许多大脑区域表现出适应(重复抑制)。一个区域的子集显示了这两种效应的重叠，其中包含对执行和观察到的运动都有选择性反应的神经元。我们在人体镜像系统的背景下描述了这些运动表征区域的功能，该系统被期望对观察到的和执行的运动做出选择性的反应。
When observing a particular movement a subset of movement-selective visual and visuomotor neurons are active in the observer's brain, forming a representation of the observed movement. Similarly, when executing a movement a subset of movement-selective motor and visuomotor neurons are active, forming a representation of the executed movement. In this study we used an fMRI-adaptation protocol to assess cortical response selectivity to observed and executed movements simultaneously. Subjects freely played the rock-paper-scissors game against a videotaped opponent, sometimes repeatedly observing or executing the same movement on subsequent trials. Numerous brain areas exhibited adaptation ( repetition suppression) during either repeated observations or repeated executions of the same movement. A subset of areas exhibited an overlap of both effects, containing neurons with selective responses for both executed and observed movements. We describe the function of these movement representation areas in the context of the human mirror system, which is expected to respond selectively to both observed and executed movements.