Taste and Smell Impairment in SARS-CoV-2 Recovers Early and Spontaneously: Experimental Data Strongly Linked to Clinical Data
Taste and Smell Impairment in SARS-CoV-2 Recovers Early and Spontaneously: Experimental Data Strongly Linked to Clinical Data
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DOI：
10.1021/acschemneuro.0c00296
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发表时间：
2020-07-15
影响因子：
5
通讯作者：
Yazici, Zahide Mine
中科院分区：
文献类型：
--
作者：
Sayin, Ibrahim;Yazici, Zahide Mine
越来越多的文献表明，在严重急性呼吸综合征(SARS)样冠状病毒(SARS-CoV-2)爆发期间，嗅觉和味觉损伤经常发生。实验研究大多发现，非神经型细胞对SARS-CoV-2相关的味觉和嗅觉损害负有责任。如果是这样的话，嗅觉/味觉障碍需要及早恢复。来自临床研究的文献数据表明，实验和临床结果之间存在很强的相关性。本文介绍了与SARS-CoV-2引起的嗅觉/味觉损伤相关的临床研究，并报告了恢复率。实验研究人员可以使用这些数据来观察气味损害的动态，并在他们的研究中实施这些发现(例如，正确的采样时间)，以进行进一步的研究。
A growing body of literature indicates that smell and taste impairment has frequently occurred during the Severe Acute Respiratory Syndrome (SARS)-like Coronavirus (SARS-CoV-2) outbreak. Experimental studies have mostly found that non-neural-type cells are responsible for SARS-CoV-2-related taste and smell impairment. If this is the case, smell/taste impairment needs to recover early. Literature data from clinical studies indicated a strong correlation between experimental and clinical findings. This article presents clinical studies related to SARS-CoV-2-induced smell/taste impairment that reported recovery rates. Experimental researchers may use these data to observe the dynamics of smell impairment and implement these findings in their research (e.g., correct timing of sampling) to perform further studies.