LEISHMANIA-TROPICA IN MOROCCO .3. IDENTIFICATION OF 89 ISOLATES FROM THE VECTOR PHLEBOTOMUS-SERGENTI
LEISHMANIA-TROPICA IN MOROCCO .3. IDENTIFICATION OF 89 ISOLATES FROM THE VECTOR PHLEBOTOMUS-SERGENTI
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DOI：
10.1051/parasite/199166396
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发表时间：
1991-01-01
期刊：
影响因子：
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通讯作者：
MARTINI, A
中科院分区：
文献类型：
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作者：
GUILVARD, E;RIOUX, JA;MARTINI, A
1989年夏季至秋季，在摩洛哥热带利什曼原虫引起的皮肤利什曼病疫源地，用CDC诱捕器捕获了7907只雌性白蛉。在白蛉属的物种中，只有塞氏白蛉具有前鞭毛体。89株菌株属于复合菌L.热带被隔离。6月份媒介生物感染频率为零，8月份上升到1.3%，10月份达到9.9%，这表明高风险时期是在炎热季节结束时。在分离的89株菌株中，74株完全分型，对应于以下四种酶组：MON-102（1株）、MON-107（56株）、MON-122（2株）和MON-123（15株）。只有前两种在人类中被观察到。酶组MON-102和MON-107在人、狗和载体中的分布非常不同。在调查的一个地点，这是强烈占主导地位的MON-107，没有涉及这种酶模式的人类病例表明存在一个野生水库。
In a Moroccan focus of cutaneous leishmaniasis caused by Leishmania tropica, 7 907 female sandflies captured with CDC traps were dissected from summer to autumn 1989. Among species of the genus Phlebotomus, only P. sergenti harbored promastigotes. Eighty-nine strains belonging to the complex L. tropica were isolated. The frequency of vector infection was zero in June, rose to 1.3% in August, and reached 9.9% in October, which indicates that the period of high risk is at the end of the hot season. Out of 89 strains isolated, 74 were completely typed and corresponded to the following four zymodemes: MON-102 (one strain), MON-107 (56 strains), MON-122 (two strains), and MON-123 (15 strains). Only the first two were observed in humans. The distribution of zymodemes MON-102 and MON-107 was very different in humans, dogs, and the vector. In one of the sites surveyed, which was strongly dominated by MON-107, the absence of human cases involving this zymodeme suggests the existence of a wild reservoir.