CAROTODYNIA
CAROTODYNIA
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DOI：
10.1212/wnl.27.1.43
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发表时间：
1977-01-01
期刊：
影响因子：
9.9
通讯作者：
PRUSINER, S
中科院分区：
文献类型：
--
作者：
RASKIN, NH;PRUSINER, S
有关颈动脉痛的病理学不确定性出现，部分原因是该综合征最初被归类为非典型面神经痛。最近，颈动脉痛的特征是反复出现的血管颈部疼痛，通常伴有颈动脉压痛和软组织肿胀，有时还伴有血管头痛。预防偏头痛的药物似乎对颈动脉痛有效。观察了8名女性(年龄39-77岁)，单侧、持续1-19年的阵发性颈部疼痛，持续时间为7个月-6年。在服用甲基舍吉、马来酸麦角新碱、心得安或去甲替林后，所有患者的疼痛症状的强度和频率都得到了显著缓解。没有患者有动脉炎的证据。偏头痛和颈动脉痛对类似药物的反应性提示了一种共同的病理生理机制。
Nosologic uncertainty about carotidynia arose, in part, because the syndrome was initially classified as an atypical facial neuralgia. More recently, carotidynia was characterized as a recurring vascular neck pain, often accompanied by carotid tenderness and soft tissue swelling and sometimes by vascular headaches. Drugs useful in the prophylaxis of migraine appeared to be effective in carotidynia. Eight women (ages 39-77 yr) with unilateral, episodic neck pain of 1-19 yr duration were observed for periods ranging from 7 mo.-6 yr. All experienced marked relief in the intensity and frequency of their pain syndromes after the adminstration of methysergide, ergonovine maleate, propranolol or nortriptyline. No patient had evidence of arteritis. The responsiveness of migraine headaches and carotidynia to similar drugs suggests a common pathophysiologic mechanism.