Structure and function of mesothelial cells.
Structure and function of mesothelial cells.
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DOI：
10.1007/978-0-387-48993-3_1
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发表时间：
2007
影响因子：
--
通讯作者：
S. Mutsaers;Sylwia Wilkosz
中科院分区：
文献类型：
--
作者：
S. Mutsaers;Sylwia Wilkosz
间皮细胞是一种特殊的细胞，排列在三个浆膜腔(胸膜、心包和腹膜)的整个表面，而在男性，间皮细胞排列在包围睾丸的囊中。这一层细胞被称为“间皮”，内脏间皮排列在内脏器官内，壁间皮排列在体壁上。间皮最早是由Bichat在1827年描述的，但直到1890年Minot才提出“间皮”一词，以反映哺乳动物中胚层腔内细胞的上皮样性质[1]。尽管早期发现和描述了间皮细胞，但直到最近几年，人们才意识到它在健康和疾病中的重要性。
Mesothelial cells are specialised cells that line the entire surface of the three serosal cavities (pleural, pericardial and peritoneal) and in the male, the sac which surrounds the testes. This layer of cells is termed ‘mesothelium’with the visceral mesothelium lining the internal organs and the parietal mesothelium lining the body wall. The mesothelium was first described by Bichat in 1827 but it was not until 1890 that Minot proposed the term ‘mesothelium’to reflect the epitheliallike nature of the cells lining the mammalian mesodermic cavities [1]. Despite the early discovery and description of the mesothelium, it has only been in recent years that its importance both in health and disease has been realised.