GENDER DIFFERENCES IN LEFT-VENTRICULAR GROWTH
GENDER DIFFERENCES IN LEFT-VENTRICULAR GROWTH
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DOI：
10.1161/01.hyp.26.6.979
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发表时间：
1995-12-01
期刊：
影响因子：
8.3
通讯作者：
MEYER, RA
中科院分区：
文献类型：
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作者：
DESIMONE, G;DEVEREUX, RB;MEYER, RA
因为人类心肌细胞的数量是在婴儿期决定的，随后左心室(LV)肌肉质量的增加反映了细胞的增大(肥大)。为了确定成年男性比女性更大的LV质量是否反映了整个发育过程中存在的性别差异，还是男性在青春期的LV不成比例增长，我们比较了333名女性和278名男性正常体重、正常血压的受试者从4个月到70岁的超声心动图LV质量。12岁以前只有很小的性别差异(平均为6%)，而在所有的老年人群中，男性的LV质量比女性大25%~38%(P
Because the number of human cardiac myocytes is determined in infancy, subsequent increases in left ventricular (LV) muscle mass reflect cellular enlargement (hypertrophy). To determine whether the greater LV mass in adult men than in women reflects sex differences that are present throughout development or disproportionate LV growth during puberty in men, we compared echocardiographic LV mass in 333 female and 278 male normal-weight, normotensive subjects from 4 months to 70 years of age. Only a small sex difference in LV mass (mean=6%) existed before age 12 years, whereas in all older-age strata LV mass in men was 25% to 38% greater than that in women (P