Salicylate Toxicity from Genital Exposure to a Methylsalicylate-Containing Rubefacient
Salicylate Toxicity from Genital Exposure to a Methylsalicylate-Containing Rubefacient
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DOI：
10.5811/westjem.2016.1.29262
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发表时间：
2016-03-01
影响因子：
3.1
通讯作者：
Erickson, Timothy B.
中科院分区：
文献类型：
--
作者：
Thompson, Trevonne M.;Toerne, Theodore;Erickson, Timothy B.
据报道，含有甲基水杨酸的润肤剂在摄入、局部应用于异常皮肤和不适当局部应用于正常皮肤后会引起水杨酸中毒。许多非处方产品含有甲基水杨酸。局部水杨酸盐在适当使用时很少产生全身毒性；然而，水杨酸甲酯可以通过完整的皮肤吸收。阴囊皮肤的吸收量是其他皮肤区域的40倍。我们报告了一个独特的水杨酸中毒的情况下，由于使用含有甲基水杨酸的润肤剂，以促进手淫在男性青少年。水杨酸盐毒性以前未见生殖器接触甲基水杨酸盐的报道。
Methylsalicylate-containing rubefacients have been reported to cause salicylate poisoning after ingestion, topical application to abnormal skin, and inappropriate topical application to normal skin. Many over-the-counter products contain methylsalicylate. Topical salicylates rarely produce systemic toxicity when used appropriately; however, methylsaliclyate can be absorbed through intact skin. Scrotal skin can have up to 40-fold greater absorption compared to other dermal regions. We report a unique case of salicylate poisoning resulting from the use of a methylsalicylate-containing rubefacient to facilitate masturbation in a male teenager. Saliclyate toxicity has not previously been reported from the genital exposure to methylsaliclyate.