Modeling for intergroup comparisons of imaging data.
Modeling for intergroup comparisons of imaging data.
复制标题
成像数据组间比较的建模。
DOI：
10.1006/nimg.1996.0058
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Woods,RP
中科院分区：
文献类型：
--
作者：
Woods,RP
Intergroup comparisons pose unique challenges in the analysis of functional imaging data. Imperfections in intersubject stereotaxis can give rise to artifactual results and make it particularly important to allow for intersubject differences in task-related changes when formulating statistical models. Because intergroup comparisons generally involve inferences about the populations from which the subjects were drawn rather than inferences about the particular subjects themselves, subjects must be treated as random rather than fixed effects in the statistical model. These requirements, when combined with the need to adjust for multiple spatial comparisons, result in low statistical power when the number of subjects in each group is small. Functional imaging studies to identify differences between groups generally require many more subjects than other types of functional imaging studies and require careful advance planning to maximize the likelihood of reaching meaningful conclusions.
