Miniaturization of photoacoustic cell for smart endoscope to improve sensitivity
Miniaturization of photoacoustic cell for smart endoscope to improve sensitivity
复制标题
智能内窥镜光声池小型化提高灵敏度
DOI：
10.1109/embc.2014.6944430
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
N. Wadamori
中科院分区：
文献类型：
--
作者：
N. Wadamori
超薄内窥镜，例如经鼻内窥镜，已经被开发用于减轻诊断和治疗期间的不适。然而，它们在可选诊断中的应用是有限的，因为许多可选诊断仪器被设计成适合通过较大的侧通道。本研究的目的是开发一种智能内窥镜，可以获得基于光声光谱的各种诊断。光声过程包括涉及光学、热和弹性过程的复杂能量转换。本工作的重点是光声传感器的缩放潜力。研制了两种不同体积的光声传感器，研究了六种不同杨氏模量硅橡胶的光声信号的幅值和频率响应。结果表明，减小传感器的体积可以增强光声信号。在内窥镜中嵌入小型化光声传感器被证实可以提高灵敏度。
Ultrathin endoscopes, such as transnasal endo-scopes, have been developed to alleviate discomfort during diagnosis and therapy. However, their application to optional diagnostics is limited since many optional diagnostic instruments are designed to fit through larger side channels. The aim of this study was to develop a smart endoscope that can obtain various diagnoses based on photoacoustic spectroscopy. The photoacoustic process comprises complex energy conversions involving optical, thermal, and elastic processes. This work focused on the scaling potential of photoacoustic sensors. Photoacoustic sensors with two different volumes were developed, and the amplitudes and frequency responses of the photoacoustic signals for silicone rubbers with six different Young's moduli were investigated. The results showed that photoacoustic signals can be enhanced by reducing the volumes of the sensors. Embedding a miniaturized photoacoustic sensor in an endoscope was confirmed to improve the sensitivity.