Natural variation at the DEP1 locus enhances grain yield in rice
Natural variation at the DEP1 locus enhances grain yield in rice
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DEP1基因座的自然变异提高了水稻的产量
DOI：
10.1038/ng.352
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发表时间：
2009-04-01
期刊：
影响因子：
30.8
通讯作者：
Fu, Xiangdong
中科院分区：
文献类型：
--
作者：
Huang, Xianzhong;Qian, Qian;Fu, Xiangdong
在许多作物中，产量受来自自然变异的数量性状基因座（QTL）控制。在这里，我们报告了一个主要的水稻籽粒产量QTL的分子特征，通过确定穗结构的行为。DEP1基因座的显性等位基因是一种功能获得性突变，导致磷脂酰乙醇胺结合蛋白样结构域蛋白的截短。该等位基因的作用是增强分生组织活性，导致花序节间长度缩短，每穗籽粒数增加，从而提高籽粒产量。该等位基因在中国高产水稻品种中很常见，可能是最近才引入栽培水稻基因库的。我们还表明，一个功能等同的等位基因是存在于温带谷物，似乎已经出现之前的分歧小麦和大麦血统。
Grain yield is controlled by quantitative trait loci (QTLs) derived from natural variations in many crop plants. Here we report the molecular characterization of a major rice grain yield QTL that acts through the determination of panicle architecture. The dominant allele at the DEP1 locus is a gain-of-function mutation causing truncation of a phosphatidylethanolamine-binding protein-like domain protein. The effect of this allele is to enhance meristematic activity, resulting in a reduced length of the inflorescence internode, an increased number of grains per panicle and a consequent increase in grain yield. This allele is common to many Chinese high-yielding rice varieties and likely represents a relatively recent introduction into the cultivated rice gene pool. We also show that a functionally equivalent allele is present in the temperate cereals and seems to have arisen before the divergence of the wheat and barley lineages.