Advances in Radiosurgery for Arteriovenous Malformations of the Brain
Advances in Radiosurgery for Arteriovenous Malformations of the Brain
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DOI：
10.1227/neu.0000000000000219
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发表时间：
2014-02-01
期刊：
影响因子：
4.8
通讯作者：
Kondziolka, Douglas
中科院分区：
文献类型：
--
作者：
Rubin, Benjamin A.;Brunswick, Andrew;Kondziolka, Douglas
大脑动静脉畸形是患者发病和死亡的重要原因。尽管我们对这种疾病的了解有所提高，但它仍然在进化中。我们治疗这些畸形的能力以及解决这些畸形的方式也有了显着改善。然而，在我们平衡治疗风险与疾病自然史时，患者临床和疾病情况的多样性常常导致我们面临具有挑战性和复杂的管理算法。本文的目的是重点回顾脑动静脉畸形的自然史，研究立体定向放射外科的作用，讨论血管内治疗与立体定向放射外科相关的作用，并展望未来的进展。
Arteriovenous malformations of the brain are a considerable source of morbidity and mortality for patients who harbor them. Although our understanding of this disease has improved, it remains in evolution. Advances in our ability to treat these malformations and the modes by which we address them have also improved substantially. However, the variety of patient clinical and disease scenarios often leads us into challenging and complex management algorithms as we balance the risks of treatment against the natural history of the disease. The goal of this article is to provide a focused review of the natural history of cerebral arteriovenous malformations, to examine the role of stereotactic radiosurgery, to discuss the role of endovascular therapy as it relates to stereotactic radiosurgery, and to look toward future advances.