RELATION BETWEEN BODY-SIZE AND BONE-MINERAL DENSITY IN ELDERLY MEN AND WOMEN
RELATION BETWEEN BODY-SIZE AND BONE-MINERAL DENSITY IN ELDERLY MEN AND WOMEN
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DOI：
10.1093/oxfordjournals.aje.a116842
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发表时间：
1993-08-01
影响因子：
5
通讯作者：
BARRETTCONNOR, E
中科院分区：
文献类型：
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作者：
EDELSTEIN, SL;BARRETTCONNOR, E
加利福尼亚州伯纳多牧场的这项横断面研究研究了 1988 年至 1991 年间 1,492 名 55-84 岁的流动白人成年人的骨矿物质密度与八项身体尺寸（总重、体重指数、腰臀比、瘦体重、脂肪量、脂肪量百分比以及当前和最大成人身高）之间的关系。通过生物电阻抗测量去脂质量、脂肪质量和脂肪质量百分比。采用双能 X 射线吸收法测量髋部和腰椎的骨矿物质密度，采用单光子吸收法测量中轴和超远端桡骨的骨矿物质密度。在根据年龄、吸烟、运动、饮酒、噻嗪类药物使用和雌激素使用（女性）进行调整的多元线性回归模型中，总重是总体骨矿物质密度最一致的标志。在该队列中，无论男女，所有身体尺寸测量值都与骨矿物质密度相关，并且是负重部位骨矿物质密度比非负重部位更好的标志，这意味着体重对骨矿物质密度的机械效应。
This cross-sectional study of the Rancho Bernardo, California, cohort examines the relation between bone mineral density and eight measures of body size (total weight, body mass index, waist-hip ratio, lean mass, fat mass, percentage fat mass, and current and maximum adult height) measured between 1988 and 1991 in 1,492 ambulatory white adults aged 55-84 years. Lean mass, fat mass, and percentage fat mass were measured by bioelectric impedance. Bone mineral density was measured at the hip and lumbar spine with dual-energy x-ray absorptiometry and at the midshaft and ultradistal radius with single photon absorptiometry. In multiple linear regression models adjusted for age, smoking, exercise, alcohol, thiazide use, and estrogen use (in women), total weight was the most consistent marker of bone mineral density overall. In this cohort, all measures of body size were associated with bone mineral density in both sexes and were better markers of bone mineral density in the weight-bearing sites than in the non-weight-bearing sites, implying a mechanical effect of weight on bone mineral density.