Ectopic gastric mucosa in proximal esophagus. Its clinical significance and hormonal profile.
Ectopic gastric mucosa in proximal esophagus. Its clinical significance and hormonal profile.
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近端食管异位胃粘膜。
DOI：
10.1097/00004836-198610000-00003
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发表时间：
1986
影响因子：
2.9
通讯作者：
P. DeRidder
中科院分区：
文献类型：
--
作者：
K. K. Shah;P. DeRidder
我们在食道近端发现异位胃粘膜20例。5名患者有症状，通常是颈部灼热感和/或吞咽困难。我们报告了胃泌素、生长抑素、血管活性肠肽和蛙皮素的免疫过氧化物酶染色结果。在接受检测的85%的活检标本中，存在一种或多种多肽。胃泌素和蛙皮素在有症状的患者中更常见，生长抑素在无症状的患者中更常见。慢性炎症改变在有症状的患者中更为常见。
We have found 20 cases of ectopic gastric mucosa in the proximal esophagus. Five patients had symptoms, usually a burning sensation in the neck and/or dysphagia. We report the results of immunoperoxidase staining of this tissue for gastrin, somatostatin, vasoactive intestinal peptide, and bombesin. In 85% of biopsy specimens tested, one or more polypeptides were present. Gastrin and bombesin were found more frequently in symptomatic patients, and somatostatin in asymptomatic patients. Chronic inflammatory changes were more frequent in symptomatic patients.