ASSESSMENT OF FAT-FREE MASS USING BIOELECTRICAL IMPEDANCE MEASUREMENTS OF THE HUMAN-BODY
ASSESSMENT OF FAT-FREE MASS USING BIOELECTRICAL IMPEDANCE MEASUREMENTS OF THE HUMAN-BODY
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DOI：
10.1093/ajcn/41.4.810
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发表时间：
1985-01-01
影响因子：
7.1
通讯作者：
LYKKEN, GI
中科院分区：
文献类型：
--
作者：
LUKASKI, HC;JOHNSON, PE;LYKKEN, GI
描述了一种用于估计人体成分的方法，该方法包括测量生物电阻抗(R)。这种方法是基于无脂肪组织块(FFM)的电导率远远大于脂肪的电导率的原理。对37例年龄28.8±-岁的健康男性进行了R测定。7.1年(平均+-。SD)，使用4电极布置的电阻抗体积描记器，将无痛信号(800微安，50千赫)引入体内。用水密度法测定FFM，范围为44.6~98.1 kg。D2O稀释法测定的全身水(TBW)和全身计数法测定的全身钾(TBK)分别为50.6±-。10.3 L和167.5。+-。分别为38.1 g。单次R测量的重测相关系数为0.99，5天以上单次测量的信度系数为0.99。R值与FFM(r=-0.86)、TBW(r=-0.86)、TBK(r=-0.79)呈线性关系。当预测因子HT2/R与FFM(r=0.98)、TBW(r=0.95)和TBK(r=0.96)进行回归时，相关系数显著增加(P<；0.01)。生物电阻抗技术是一种可靠、有效的人体成分估计方法。该方法安全、非侵入性、测量速度快、不需要操作者的熟练操作和专业人员的协作，而且便于携带。建议在身体成分异常的受试者中进一步验证该方法。
A method which involves the measurement of bioelectrical resistive impedance (R) for the estimation of human body composition is described. This method is based upon the principle that the electrical conductivity of the fat-free tissue mass (FFM) is far greater than that of fat. Determinations of R were made in 37 healthy men aged 28.8 .+-. 7.1 yr (mean .+-. SD) using an electrical impedance plethysmograph with a 4 electrode arrangement that introduces a painless signal (800 .mu.A at 50 kHz) into the body. FFM was assessed by hydrodensitometry and ranged from 44.6-98.1 kg. Total body water (TBW) determined by D2O dilution and total body potassium (TBK) from whole body counting were 50.6 .+-. 10.3 L and 167.5 .+-. 38.1 g, respectively. Test retest correlation coefficient was 0.99 for a single R measurement and the reliability coefficient for a single R measurement over 5 days was 0.99. Linear relationships were found between R values and FFM (r = -0.86), TBW (r = -0.86), and TBK (r = -0.79). Significant (P < 0.01) increases in the correlation coefficients were observed when the predictor Ht2/R was regressed against FFM (r = 0.98), TBW (r = 0.95), and TBK (r = 0.96). The bioelectrical impedance technique is a reliable and valid approach for the estimation of human body composition. This method is safe, noninvasive, provides rapid measurements, requires little operator skill and subject cooperation, and is portable. Further validation of this method is recommended in subjects with abnormal body composition.