A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging
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用于半胱氨酸检测的选择性荧光传感器,具有作为活细胞成像中的白光发射荧光团的潜力

DOI:
10.1039/c9tb00273a
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发表时间:
2019-05
影响因子:
7
通讯作者:
Hai-Liang Zhu
Hai-Liang Zhu
中科院分区:
工程技术2区
文献类型:
--
作者:
Yu-Shun Yang;Zeng-Hui Yuan;Xu-Ping Zhang;Jian-Fei Xu;Peng-Cheng Lv;Hai-Liang Zhu

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A novel fluorescent sensor CysW-1 was introduced for cysteine.detection via the cleavage reaction of two fluorophores. It exhibited.advantages including high sensitivity, high selectivity and low toxicity..By optimizing the conditions, a relatively steady and practical white.light emitting system was successfully generated. The system was.applicable in a wide pH range (7.0–12.0) and a long period (over 12 h)..The most attractive point of CysW-1 was its biocompatibility, which.ensured the application of the white light emitting system in living cell.imaging and further pre-clinical potential.
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