WRKY: its structure, evolutionary relationship, DNA-binding selectivity, role in stress tolerance and development of plants
WRKY: its structure, evolutionary relationship, DNA-binding selectivity, role in stress tolerance and development of plants
复制标题
DOI：
10.1007/s11033-010-0504-5
复制
发表时间：
2011-08-01
影响因子：
2.8
通讯作者：
Chikara, Jitendra
中科院分区：
文献类型：
--
作者：
Agarwal, Parinita;Reddy, M. P.;Chikara, Jitendra
植物在其固着、自养的生活方式中受到广泛的环境信号的影响，并在转录因子的帮助下调节复杂的基因表达模式。WRKY转录因子被认为是植物特有的，然而，在原生生物、黏菌、蕨类和松树中也有报道。WRKY的名字来源于其高度保守的60个氨基酸的长WRKY结构域。这些转录因子显示W盒特异结合，这也受W盒侧翼序列的影响。在进化过程中，该家族以不同的模式扩展，以促进植物在细胞、发育和生理上的不同作用。WRKY转录因子是开花植物中最大的家族之一，在植物防御调节、非生物胁迫以及参与植物生长发育等方面发挥着广泛的调节作用。
The plants during their sessile, autotrophic lifestyle are affected by wide range of environmental signals and regulate complex patterns of gene expression with the help of transcription factors. The WRKY transcription factors are considered as plant-specific, however, are also reported in protist, slime mold, fern and pine. The WRKY name is coined from its highly conserved 60 amino acid long WRKY domain. These TFs show W box specific binding which is also influenced by the W box flanking sequence. During evolution, the family has expanded in different patterns to facilitate distinct cellular, developmental, and physiological role in plants. The WRKY TFs form one of the largest families in flowering plants, and play a broad spectrum regulatory role as positive and negative regulators of plant defense regulation, abiotic stresses and also involved in growth and development of plants.