The Non-Protein Amino Acids
The Non-Protein Amino Acids
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非蛋白质氨基酸
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
S. Hunt
中科院分区：
文献类型：
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作者：
S. Hunt
1961年，格林斯坦和温尼茨列出了大约90种非蛋白质来源的氨基酸或亚胺酸。今天随便找一个见多识广的生物学家，他可能会告诉你，目前已知的天然氨基酸大概有200种左右。事实上，这将是一个严重的低估，因为本章所附的表格接近700种氨基酸和亚胺酸或相关衍生物。作者并没有声称他已经穷尽了他的文献检索（尽管筋疲力尽），新化合物的发现速度使它很可能有许多将被忽视。的确，现在已知的天然氨基酸如此之多，“重新发现”一定会成为一件司空见惯的事情。目前迫切需要一份全面的结构、来源、化学和生物特性的目录，但本综述并不期望实现这一功能。然而，这可能是为尚未从文献中清除的遗漏分子、错误结构和虚假化合物道歉的关键。
In 1961 Greenstein and Winitz [1] listed some ninety amino or imino acids of non-protein origin. Scratch a reasonably well-informed biologist today and he might tell you that there are probably about two hundred natural amino acids now known. In fact this would be a wild underestimate since the tables appended to this chapter list close upon seven hundred amino and imino acids or related derivatives. The author makes no claim to have been exhaustive (though exhausted) in his literature search and the pace of discovery of new compounds makes it highly likely that many will have been overlooked. Indeed there are now so many natural amino acids known that ‘rediscovery’ must be becoming a common event. A comprehensive catalogue of structures, sources, chemical and biological properties is badly needed but this review does not aspire to that function. This is however perhaps the point to apologize for missed molecules, erroneous structures and spurious compounds not yet purged from the literature.